Study types
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- adenomyosis 7
- endometriosis 5
- mesh:D004715 3
- chronic_pelvic_pain 2
- infertility 2
- dysmenorrhea 1
- dyspareunia 1
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Frequent coauthors
- Wen-Xiu Cheng 4
- Li Huang 3
- Yan Wang 3
- Yu Shao 3
- Tongtong Zeng 2
- Hongjun Li 2
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Oxidative stress plays a central role in reproductive disorders, with food bioactive compounds offering therapeutic potential through their antioxidant properties. This review examines antioxidant active ingredients from plant-based foods a…
目的 探讨内异康复片对小鼠子宫腺肌病纤维化的影响,并探讨其对IL-6/STAT3信号通路的调控作用。 方法 采用枸橼酸他莫昔芬滴喂的方法制备子宫腺肌病纤维化小鼠模型,70日龄小鼠采用低、中、高剂量的内异康复制剂及地诺孕素分别给药治疗,灌胃期间比较各组小鼠不同时间段的热痛阈值,灌胃治疗8周后取样,HE及Masson染色观察子宫组织病理学,Western Blot检测小鼠子宫组织中STAT3、p-STAT3的蛋白表达含量,ELISA测定血清中IL-6、TGF-β1、MCP-…
目的 探索内异康复片通过JAK2/STAT3通路调控子宫腺肌病小鼠巨噬细胞极化的作用机制。 方法 将造模成功的子宫腺肌病小鼠随机分为模型组、内异康复低/中/高剂量组、地诺孕素组。另设对照组。干预8周。采用热测痛仪评估疼痛敏感度;HE染色观察子宫病理形态;RT-qPCR和Western blot测定JAK2/STAT3通路相关因子mRNA的表达及磷酸化水平;免疫组化分析iNOS、Arg-1、IL-12A、IL-10的表达差异。 结果 模型组小鼠痛觉敏感度升高(P<0.…
This review examines the neurobiological mechanisms by which plant-derived compounds influence women's reproductive health through the neuroendocrine-reproductive axis. Gynecological disorders frequently present with neurological manifestat…
In various hyperproliferative disorders, damaged mitochondria can release mitochondrial DNA (mtDNA) into the cytoplasm, activating the cGAS-STING signaling pathway and subsequent immune imbalances. Our previous research has demonstrated tha…
BACKGROUND: Surgical management of endometriosis can be carried out with the traditional standard laparoscopic technique or the robotic surgery technique; however, it is not clear if there is a significant difference between techniques. Thi…
Adenomyosis is a common benign gynecological disorder and an important factor leading to infertility in fertile women. Adenomyosis can cause deep lesions and is persistent and refractory in nature due to its tumor-like biological characteri…
BACKGROUND: Chronic pelvic pain (CPP) is one of the common sequela of pelvic inflammatory disease, the pathological factors are adhesions, scarring and pelvic congestion which caused by inflammation, often cause abdominal pain and lumbosacr…
BACKGROUND: Adenomyosis is benign gynecologic condition with complex etiologies. Common symptoms associated with adenomyosis (AM) include menorrhagia, dysmenorrhea, chronic pelvic pain, metrorrhagia, and dyspareunia. Although Chinese herbal…
OBJECTIVE: To explore the different effects of rectal application of Neiyi Kangfu Suppository (NYKFS) on the expressions of cytochrome C (Cyt C) and Survivin in ectopic and eutopic endometrium in endometriosis (EMT) model rats. METHODS: EMT…