Aline Amaro dos Santos

other 2022

Comparative metabolomic profiling of women undergoing in vitro fertilization procedures reveals potential infertility-related biomarkers in follicular fluid

Scientific reports ·doi:10.1038/s41598-022-24775-5

Infertility is a worldwide concern, affecting one in six couples throughout their reproductive period. Therefore, enhancing the clinical tools available to identify the causes of infertility may save time, money, and emotional distress for …

observational 2022

Folate metabolism abnormalities in infertile patients with endometriosis

Biomarkers in medicine ·doi:10.2217/bmm-2021-0076

Background: Homocysteine levels can be impacted by enzymes variations. Aim: To correlate MTHFR, MTR and MTRR variants with homocysteine levels in the blood and follicular fluid and assisted reproduction results. Material & methods:MTHFR (rs…

nonrandomized-trial 2014

Analysis of FokI polymorphism of vitamin D receptor gene in intervertebral disc degeneration

Genetic testing and molecular biomarkers ·doi:10.1089/gtmb.2014.0030

AIM: We have hypothesized a possible relationship between disc degeneration (DD) and VDR FokI/T2C polymorphism. METHODS: A case-control study was performed comprising 121 Brazilian patients with confirmed DD by nuclear magnetic resonance a…

2013

Polymorphisms in the CYP2C19 and Hsd17b1 genes associated to estrogen metabolism in women with endometriosis

·doi:10.1016/j.fertnstert.2013.07.768

observational 2013

There is no relationship between Paraoxonase serum level activity in women with endometriosis and the stage of the disease: an observational study

Reproductive health ·doi:10.1186/1742-4755-10-32

BACKGROUND: Endometriosis is a chronic condition whose pathophysiology is unknown, but there is evidence suggesting a link with oxidative stress. Paraoxonase is a serum enzyme which circulates associated with high-density lipoprotein (HDL).…