Mahera Al-Akoum — Endo Lab

lab-animal 2016

Augmented Angiogenic Factors Expression via FP Signaling Pathways in Peritoneal Endometriosis

The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2016-1569

CONTEXT: Angiogenesis is required for ectopic endometrial tissue growth. Our previous studies showed that prostaglandin F2α (PGF2α) biosynthetic enzymes and receptor were markedly elevated in endometriotic lesions and that PGF2α is a potent…

observational 2016

Promotion of angiogenesis and proliferation cytokines patterns in peritoneal fluid from women with endometriosis

Journal of Reproductive Immunology ·doi:10.1016/j.jri.2016.01.005

Studies have long sought specific cytokines that could characterize endometriosis. Either due to variations between study designs regarding the assessment criteria for the cytokine or to low power resulting from small sample size, no factor…

observational 2014

Blood soluble interleukin 1 receptor accessory protein levels are consistently low throughout the menstrual cycle of women with endometriosis

Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-12-51

BACKGROUND: A deficiency in the counter-regulatory mechanisms of interleukin 1 (IL1) may play a significant role in endometriosis pathogenesis and associated chronic inflammation. The aim of this study was to investigate peripheral blood le…

observational 2006

Macrophage migration inhibitory factor expression in the intrauterine endometrium of women with endometriosis varies with disease stage, infertility status, and pelvic pain

Fertility and sterility ·doi:10.1016/j.fertnstert.2005.10.073

OBJECTIVE: To evaluate the concentrations of macrophage migration inhibitory factor (MIF) in the eutopic endometrial tissue of women with and without endometriosis. DESIGN: Retrospective study using ELISA to measure MIF concentrations in t…