OBJECTIVE: The analgesic efficacy and safety of transversus abdominis plane block (TAPB) and thoracic paravertebral block (TPVB) were compared following laparoscopic total hysterectomy (LTH), and whether their treatment effects differ by fr…
Endometriosis (EMs) is a chronic inflammatory disease characterized by ectopic growth of endometrial-like tissues. N6-methyladenosine (m6A) modification regulates diverse cellular processes, yet its role in EMs remains unclear. Here, we sho…
Endometriosis (EMs) is an estrogen-dependent chronic inflammatory gynecological disease characterized by ectopic growth of endometrial tissues, leading to dysmenorrhea, pelvic pain, and infertility. Although the retrograde menstruation theo…
Endometriosis is an estrogen-dependent chronic inflammatory disorder. Cholesterol (CHO) has been reported to be closely associated with estrogen synthesis and inflammatory responses. Nevertheless, the mechanisms underlying the effects of ch…
Endometriosis, an estrogen-dependent inflammatory disorder prevalent in reproductive-age women, is characterized by the growth of endometrial-like tissue outside the uterine cavity, leading to chronic pain and infertility. Current therapeut…
Infertility impacts 48 million couples globally, and accumulating evidence suggests that micronutrients potentially influence reproductive health. This Mendelian randomization study investigates causal relationships between 15 micronutrient…
RESEARCH QUESTION: To investigate the underlying mechanisms driving the opposing effects of transforming growth factor-beta 1 (TGFβ1) on the proliferation of control (CESCs) and ectopic (EESCs) endometrial stromal cells. DESIGN: Cell proli…
Growing research suggests that endometriosis and systemic lupus erythematosus (SLE) are both chronic inflammatory diseases and closely related, but no studies have explored their common molecular characteristics and underlying mechanisms. B…
Growing evidence indicates that the tumor biomarker cytokeratin 19 fragment (CYFRA21-1) is significant for a variety of cancers. However, its role in epithelial ovarian cancer (EOC) has rarely been reported. In this study, a receiver operat…