Guang Xin

No ORCID on file · 3 papers in corpus
lab-animal 2025
Eriodictyol from Scutellariae Barbata alleviates inflammation and necrosis via ZBP1-dependent signaling in acute pancreatitis
Phytomedicine : international journal of phytotherapy and phytopharmacology ·doi:10.1016/j.phymed.2025.156926

BACKGROUND: Acute pancreatitis (AP) is an inflammatory disease of the pancreas marked by inflammation and acinar cell necrosis. Scutellariae Barbata (S. Barbata), a traditional Chinese herb for inflammation, has unclear efficacy for AP. PU…

other 2023
Calcium/P53/Ninjurin 1 Signaling Mediates Plasma Membrane Rupture of Acinar Cells in Severe Acute Pancreatitis
International journal of molecular sciences ·doi:10.3390/ijms241411554

Ninjurin 1 (NINJ1) is a double-transmembrane cell-surface protein that might mediate plasma membrane rupture (PMR) and the diffusion of inflammatory factors. PMR is a characteristic of acinar cell injury in severe acute pancreatitis (SAP). …

other 2021
Vitamin B12 Attenuates Acute Pancreatitis by Suppressing Oxidative Stress and Improving Mitochondria Dysfunction via CBS/SIRT1 Pathway
Oxidative medicine and cellular longevity ·doi:10.1155/2021/7936316

Acute pancreatitis is an inflammatory disorder of the pancreas associated with substantial morbidity and mortality, which is characterized by a rapid depletion of glutathione (GSH). Cysthionine-β-synthase (CBS) is a key coenzyme in GSH synt…