Armendariz-Borunda J

ORCID: 0000-0002-7101-9943 · 1 paper in corpus

other 2026

Aberrant STAT3 activation and overproduction of IL-21 in systemic lupus erythematosus: role of miR-155 and miR-21 in target genes SOCS1, PTEN and PIAS3

Frontiers in immunology ·doi:10.3389/fimmu.2026.1664409

INTRODUCTION: SLE is a chronic autoimmune disease characterized by immune system dysregulation, including aberrant activation of B and T lymphocytes and overproduction of proinflammatory cytokines such as IL-21. Through the STAT3 signaling …