Yedong Tang

No ORCID on file · 5 papers in corpus
lab-animal 2025
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.2504361122

Progesterone receptor (PR)-mediated progesterone (P4) signaling plays a crucial role in the establishment of uterine receptivity which is the prerequisite for successful embryo implantation in mammals. However, detailed molecular mechanisms…

lab-animal 2023
Journal of ovarian research ·doi:10.1186/s13048-023-01215-0

BACKGROUND: Traditional Chinese medicine has been used for a long time to treat a variety of gynecological diseases. Among various traditional Chinese medicine, Dingkun Pill (DK) has been used for the treatment of female gynecological disea…

lab-animal 2023
EBioMedicine ·doi:10.1016/j.ebiom.2022.104433

BACKGROUND: Successful embryo implantation requires the attachment of a blastocyst to the receptive endometrial epithelium, which was disturbed in the women with recurrent implantation failure (RIF). Endometrial β3-integrin was the most imp…

lab-animal 2022
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.2206000119

Estrogen and progesterone specify the establishment of uterine receptivity mainly through their respective nuclear receptors, ER and PR. PR is transcriptionally induced by estrogen-ER signaling in the endometrium, but how the protein homeos…

lab-animal 2020
Journal of molecular endocrinology ·doi:10.1530/jme-19-0100

Decidualization is a critical process for embryo implantation and pregnancy maintenance in humans. The homeobox gene HOXA10 has been widely studied in endometrial receptivity establishment and decidualization. MEIS1, a three-amino-acid loop…