Sascha Ott

ORCID: 0000-0002-5411-8114 · 5 papers in corpus
lab-animal 2024
·doi:10.1101/2024.03.07.583861

Abstract Endometriosis negatively impacts the health-related quality of life of 190 million women worldwide. Novel advances in non-hormonal treatments for this debilitating condition are desperately needed. Macrophages play a vital role in …

lab-animal 2024
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.2405474121

Endometriosis negatively impacts the health-related quality of life of 190 million women worldwide. Novel advances in nonhormonal treatments for this debilitating condition are desperately needed. Macrophages play a vital role in the pathop…

lab-animal 2020
Frontiers in cell and developmental biology ·doi:10.3389/fcell.2020.567610

Endometrial mesenchymal stem cells (eMSC) drive the extraordinary regenerative capacity of the human endometrium. Clinical application of eMSC for therapeutic purposes is hampered by spontaneous differentiation and cellular senescence upon …

lab-animal 2018
FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fj.201701098r

Spontaneous decidualization of the endometrium in response to progesterone signaling is confined to menstruating species, including humans and other higher primates. During this process, endometrial stromal cells (EnSCs) differentiate into …

lab-animal 2017
Scientific reports ·doi:10.1038/s41598-017-11674-3

Embryo implantation requires a hospitable uterine environment. A key metabolic change that occurs during the peri-implantation period, and throughout early pregnancy, is the rise in endometrial glycogen content. Glycogen accumulation requir…