Blokzijl H

No ORCID on file · 2 papers in corpus

rct 2026

Effects of the GnRH agonist leuprorelin on liver volume in premenopausal women with severe polycystic liver disease.

Hepatology communications ·doi:10.1097/hc9.0000000000001067

BackgroundPolycystic liver disease (PLD) is characterized by multiple liver cysts, sometimes leading to severe liver enlargement, with associated physical and psychosocial complaints. Treatment options are limited. Female gender is a risk f…

other 2022

Protocol for a randomized controlled multicenter trial assessing the efficacy of leuprorelin for severe polycystic liver disease: the AGAINST-PLD study

BMC gastroenterology ·doi:10.1186/s12876-022-02142-y

BACKGROUND: In patients with severe polycystic liver disease (PLD), there is a need for new treatments. Estrogens and possibly other female sex hormones stimulate growth in PLD. In some patients, liver volume decreases after menopause. Fema…