Rodica Maricela Anghel

Background: Tumour mutational burden (TMB) is increasingly recognized as a vital biomarker for predicting the efficacy of immune checkpoint inhibitors (ICIs) in cancer treatment. Despite its growing importance, the effectiveness of TMB as …

BACKGROUND: Vascular endothelial growth factor (VEGF) plays an important role in tumor progression in ovarian cancer, but the complex mechanism and interaction with oxidative stress are not fully understood. METHODS: A prospective study in…

The microbiota is the complex community of microorganisms that populate a particular environment in the human body, whereas the microbiome is defined by the entire habitat-microorganisms and their environment. The most abundant and, therefo…

Background: Hypoxia plays an important role in ovarian cancer and understanding the role of reactive oxygen species and VEGF may identify patients who benefit the most from targeted therapies. The aims of the study were to determine the int…