Robert B. Jaffe

No ORCID on file · 4 papers in corpus
nonrandomized-trial 1997
Dose-related suppression of serum luteinizing hormone in women by a potent new gonadotropin-releasing hormone antagonist (Ganirelix) administered by intranasal spray
Fertility and sterility ·doi:10.1016/s0015-0282(97)80071-4

OBJECTIVE: To determine if the GnRH antagonist (GnRH-a) Ganirelix (Syntex Research, Palo Alto, CA), administered by intranasal (IN) spray to normal women, is absorbed into the systemic circulation and suppresses LH secretion. DESIGN: A sin…

lab-animal 1996
Ovarian steroid regulation of vascular endothelial growth factor in the human endometrium: implications for angiogenesis during the menstrual cycle and in the pathogenesis of endometriosis
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.81.8.8768883

The human endometrium undergoes a complex process of vascular and glandular proliferation, differentiation, and regeneration with each menstrual cycle in preparation for implantation. Vascular endothelial growth factor (VEGF) is an endothel…

1987
Clinical Investigations of the Contraceptive and Therapeutic Potential of Nafarelin
·doi:10.1007/978-94-009-3229-6_17
other 1985
Treatment of endometriosis with a potent agonist of gonadotropin-releasing hormone (nafarelin)
Fertility and sterility ·doi:10.1016/s0015-0282(16)48970-3

Administration of superactive agonistic analogs of gonadotropin-releasing hormone (GnRH) has been shown to induce a paradoxic and reversible suppression of gonadotropins, resulting in suppressed gonadal steroid concentrations. Because there…