Robert S. Schenken

No ORCID on file · 89 papers in corpus · active 1978-2024

Study types

  • article 75
  • review 5
  • other 4
  • letter 2
  • editorial 1

Condition tags

  • endometriosis 44
  • mesh:D004715 36
  • infertility 6
  • mesh:D017699 1
  • endometrioma 1
article 2024
HYALURONIC ACID SYSTEM IN RHESUS MONKEYS AS A MODEL FOR STUDYING THE PATHOGENESIS OF EARLY ENDOMETRIOTIC LESIONS
·doi:10.1016/j.fertnstert.2024.07.120
article 2023
EFFECTS OF THE ERβ AGONIST LY ON ATTACHMENT AND INVASION OF ENDOMETRIAL CELLS
·doi:10.1016/j.fertnstert.2023.08.420
preprint 2021
Endometrial Gap Junction Expression - Early Indicators of Endometriosis and Integral to Invasiveness
·doi:10.1101/2021.01.25.428135

Abstract Endometriosis is an invasive disease, and a leading cause of pain, infertility and disability among women, with an incidence 10 fold that of cancer. A more complete understanding of disease pathogenesis is essential for the develop…

article 2021
HYALURONIC ACID PATHWAY EXPRESSION IN ESTROGEN-PROGESTERONE TREATMENT AND PROGESTERONE ONLY TREATMENT OF ENDOMETRIOSIS
·doi:10.1016/j.fertnstert.2021.07.569
article 2021
HYALURONIC ACID PATHWAY EXPRESSION IN PAIRED EUTOPIC ENDOMETRIAL AND ENDOMETRIOMA CELLS
·doi:10.1016/j.fertnstert.2021.07.555
article 2020
CD44 variant 6 is involved in the attachment and invasion of endometrial cells to peritoneum
F&S science ·doi:10.1016/j.xfss.2020.08.002

Objective To study the effects of CD44 standard (CD44s), CD44v3, and CD44v6 overexpression (OE) on immortalized human endometrial epithelial (iEECs) and stroma cells (human endometrial stromal cells [hESCs]) using in vitro assays and a nude…

article 2020
EFFECT OF IL-6 AND TNF ALPHA ON INVASION OF EPITHELIAL AND STROMAL ENDOMETRIAL CELLS IN AN IN VITRO MODEL OF HUMAN PERITONEUM
·doi:10.1016/j.fertnstert.2020.08.1064
article 2020
Inhibition of Hyaluronic Acid Synthesis Decreases Endometrial Cell Attachment, Migration, and Invasion
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-019-00100-w
article 2019
3332 Overexpression of CD44 is involved in the development of the early endometriotic lesion in a xenograft model
·doi:10.1017/cts.2019.255

OBJECTIVES/SPECIFIC AIMS: Previously, we showed decreased development of endometriotic lesions in CD44 knockout mice compared to control.(1) CD44 has 10 different variants and a standard form. Menstrual endometrial cells (MECs) from women w…

article 2019
Overexpression of CD44v6 is involved in the development of the early endometriotic lesion in a xenograft model
·doi:10.1016/j.fertnstert.2019.07.941
article 2018
Endometrial attachment and invasion is decreased with estrogen receptor beta knock down
·doi:10.1016/j.fertnstert.2018.07.1105
article 2018
Endometrial cell invasion is decreased with inhibition of hyaluronic acid synthesis
·doi:10.1016/j.fertnstert.2018.07.1094
article 2018
Knockdown of cd44 decreases attachment but not invasion of endometrial epithelial cells
·doi:10.1016/j.fertnstert.2018.07.1089
article 2018
Overexpression of CD44 is involved in the development of the early endometriotic lesion
·doi:10.1016/j.fertnstert.2018.07.1090
article 2018
The Hyaluronic Acid System is Intact in Menstrual Endometrial Cells in Women With and Without Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719118766257
article 2017
2114
Journal of clinical and translational science ·doi:10.1017/cts.2017.203

OBJECTIVES/SPECIFIC AIMS: To further elucidate the role of estrogen receptor β (ER-β) in the early endometriotic lesion attachment. METHODS/STUDY POPULATION: EECs were immortalized using a telomerase vector. Immortalized cells and parental …

article 2017
The role of estrogen receptor beta in development of the early endometriotic lesion
·doi:10.1016/j.fertnstert.2017.07.589
article 2015
Endometriosis and Lipid Concentration
·doi:10.1097/01.aog.0000463619.54777.2f

OBJECTIVE: Endometriosis affects 5–10% of reproductive-aged women. The exact etiology is poorly understood. Oxidative stress and intrinsic inflammatory status are associated with the development and progression of endometriosis. Atheroscler…

article 2015
Impaired Development of Early Endometriotic Lesions in CD44 Knockout Mice
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719115594022
article 2014
Abstract 3326: Parallel EMT pathways mediated by epidermal growth factor, EpCAM and mesenchymal cadherins in benign endometriotic lesions and endometrial cancer
·doi:10.1158/1538-7445.am2014-3326

Abstract The endometrium is the major target of oncogenesis in the uterus. Endometrial tissue undergoes several cycles of disintegration and repair during women's reproductive years. The involvement of repair mechanisms that include transfo…

article 2014
Endometrial epithelial cell expression of estrogen receptor isoforms alpha and beta alters attachment to peritoneal mesothelial cells
·doi:10.1016/j.fertnstert.2014.07.988
article 2013
Ovarian steroid alter endometrial epithelial cell attachment to peritoneal mesothelial cells
·doi:10.1016/j.fertnstert.2013.07.773
article 2012
Increased expression of macrophage colony–stimulating factor and its receptor in patients with endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2012.02.007
article 2012
Long-term management of symptoms of endometriosis: Surgery vs medical therapy for endometriosis: Risks and benefits
article 2012
Raf-1, a Potential Therapeutic Target, Mediates Early Steps in Endometriosis Lesion Development by Endometrial Epithelial and Stromal Cells
Endocrinology ·doi:10.1210/en.2011-1879

Endometriosis is a hormone-sensitive gynecological disorder characterized by the benign growth of endometrial-like tissue in the pelvic cavity. Endometriotic lesions composed of endometrial stromal cells (ESC) and glandular epithelial cells…