Metabolic determinants of oocyte quality and embryonic development remain incompletely understood. Here, we profiled metabolites in human cumulus cells (CCs) and follicular fluid (FF), validated in two mouse models, and integrated transcrip…
INTRODUCTION: Primary omental pregnancy (OP) is very rare, and achieving an accurate diagnosis has always been a challenge for obstetricians, gynecologists, and sonographers. Our attempt to utilize intraoperative ultrasonography has facilit…
BACKGROUND: Dysmenorrhea and menstrual disorders caused by endometriosis (EM) and adenomyosis (AM) have significantly affected the quality of life of a large number of women. As a highly effective clinical contraceptive measure, etonogestre…
RATIONALE: The coexistence of intrauterine and extrauterine pregnancies is termed heterotopic pregnancy (HP). Most reported cases of HP occur after assisted reproductive technology, and HP in a natural pregnancy (NP) is very rare, often dis…
BACKGROUND: The objective of this study was to assess the trade-off between cycle continuation and cancellation in slow ovarian response (SOR) patients, and to evaluate the impact of SOR on embryo developmental potential and clinical pregna…
BACKGROUND: Nicotinamide (NAM) is an important antioxidant, which is closely related to female fertility, but its role has not been clearly elucidated. The purpose of the present study was to investigate the effects of NAM on follicular dev…
BACKGROUND: To investigate the metabolic profiles in the follicular fluid (FF) samples from patients undergoing in vitro fertilization (IVF) and to analyze the correlations with follicular development. METHODS: The FF samples were obtained…