Laurel Gillette

Endosalpingiosis (ES) and endometriosis (EM) refer to the growth of tubal and endometrial epithelium respectively, outside of their site of origin. We hypothesize that uterine secretome factors drive ectopic growth. To test this, we develop…

Endometriosis is a debilitating gynecologic disorder that affects ∼10% of women of reproductive age. Endometriosis is characterized by growth of endometriosis lesions within the abdominal cavity, generally thought to arise from retrograde m…

Abstract Endometriosis is an invasive disease, and a leading cause of pain, infertility and disability among women, with an incidence 10 fold that of cancer. A more complete understanding of disease pathogenesis is essential for the develop…

Abstract High grade serous carcinoma (HGSC) arises from the ectopic implantation of malignant oviductal epithelial cells (OECs) in the peritoneal cavity and on the ovarian surface (the “tubal origins hypothesis”). We believe that these cell…