Zongfeng Zhang

Endometriosis (EMs) features ectopic implantation of endometrial stromal cells (EESCs) and strong anoikis resistance, yet how inflammatory signals reprogram mitochondrial function remains unclear. Here, neutrophil extracellular traps (NETs)…

Long non-coding RNA Urothelial carcinoma-associated 1 (UCA1) is a pivotal regulator in the progression of endometriosis (EMs), yet its mechanistic role remains elusive. This study identified UCA1 as a factor promoting glycolysis through bio…

Endometriosis (EMs) is a chronic gynecologic condition characterized by the growth of endometrial stromal and glandular tissue outside the uterine cavity of unknown etiology. Currently, ferroptosis resistance, increased glycolysis, and incr…

Endometriosis (EMs) is a chronic, estrogen-dependent disease defined by the presence of endometrial-like tissue outside the uterine cavity. Gut microbiota has emerged as potent inducer for chronic inflammatory disease, yet whether its mecha…

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Abstract Background Insulin like growth factor II mRNA binding protein 3 (IGF2BP3) has been implicated in numerous inflammatory and cancerous conditions. However, its precise molecular mechanisms in endometriosis (EMs) remains unclear. The …

BACKGROUND: Insulin like growth factor II mRNA binding protein 3 (IGF2BP3) has been implicated in numerous inflammatory and cancerous conditions. However, its precise molecular mechanisms in endometriosis (EMs) remains unclear. The aim of t…

Abstract Background Insulin like growth factor II mRNA binding protein 3 (IGF2BP3) has been implicated in numerous inflammatory and cancerous conditions. However, its precise molecular mechanisms in endometriosis (EMs) remains unclear. The …

Endometriosis is a gynecological inflammatory disease that is linked with immune cells, specifically macrophages. IL-33 secreted from macrophages is known to accelerate the progression of endometriosis. The periodic and repeated bleeding th…

Abstract Endometriosis is a gynecological inflammatory disease which linked with immune cells, specifically macrophages. And IL-33 secreted from macrophages is known to accelerate the progression of endometriosis. The periodic and repeated …

Additional file 1: Fig. S1. Identification of primary endometriotic stromal cells (ESCs). ESCs were identified by immunofluorescent staining for vimentin (+) and cytokeratin 7 (-).

Additional file 1: Fig. S1. Identification of primary endometriotic stromal cells (ESCs). ESCs were identified by immunofluorescent staining for vimentin (+) and cytokeratin 7 (-).

Additional file 2: Fig. 2. Validation of transfection efficiency. (A) Transfection efficiency of si-CCR6 assessed by qRT-PCR. (B) Transfection efficiency of TFEB-OE assessed by qRT-PCR. (C) Transfection efficiency of Ad-LC3 at different MOI…

Additional file 2: Fig. 2. Validation of transfection efficiency. (A) Transfection efficiency of si-CCR6 assessed by qRT-PCR. (B) Transfection efficiency of TFEB-OE assessed by qRT-PCR. (C) Transfection efficiency of Ad-LC3 at different MOI…

Additional file 3: Fig. 3. Expression of related signaling pathway genes in ESCs in response to activation of CCL20/CCR6 axis. (A) The protein level of different signaling genes in ESCs in response to activation of CCL20/CCR6 axis by wester…

Additional file 3: Fig. 3. Expression of related signaling pathway genes in ESCs in response to activation of CCL20/CCR6 axis. (A) The protein level of different signaling genes in ESCs in response to activation of CCL20/CCR6 axis by wester…

Abstract Background Endometriosis (EMs) is a common benign gynecological disease that affects approximately 10% of females of reproductive age. Endometriosis ectopic lesions could recruit macrophages, which in turn facilitates endometriosis…