van den Berg M

No ORCID on file · 3 papers in corpus
rct 2026
Effects of the GnRH agonist leuprorelin on liver volume in premenopausal women with severe polycystic liver disease.
Hepatology communications ·doi:10.1097/hc9.0000000000001067

BackgroundPolycystic liver disease (PLD) is characterized by multiple liver cysts, sometimes leading to severe liver enlargement, with associated physical and psychosocial complaints. Treatment options are limited. Female gender is a risk f…

other 2022
Protocol for a randomized controlled multicenter trial assessing the efficacy of leuprorelin for severe polycystic liver disease: the AGAINST-PLD study
BMC gastroenterology ·doi:10.1186/s12876-022-02142-y

BACKGROUND: In patients with severe polycystic liver disease (PLD), there is a need for new treatments. Estrogens and possibly other female sex hormones stimulate growth in PLD. In some patients, liver volume decreases after menopause. Fema…

observational 2016
Relative effect potency estimates of dioxin-like activity for dioxins, furans, and dioxin-like PCBs in adults based on cytochrome P450 1A1 and 1B1 gene expression in blood
Environment international ·doi:10.1016/j.envint.2016.08.016

BACKGROUND: In the risk assessment of PCDDs, PCDFs, and dioxin-like (DL) PCBs, regulatory authorities support the use of the toxic equivalency factor (TEF)-scheme derived from a heterogeneous data set of the relative effect potency (REPs) e…