Jian Chen

BACKGROUND: Emerging evidence implicates the gut microbiota in the pathogenesis of adenomyosis (AM); however, whether this association is causal and through which mechanisms it operates remain largely unknown. METHODS: To interrogate poten…

BACKGROUND: Deep infiltrating endometriosis is a subtype of endometriosis. A case of retroperitoneal endometriosis surrounding the ureter and forming a pelvic mass is relatively rare. CASE PRESENTATION: A 26-year-old woman was admitted to …

BACKGROUND: Cesarean scar pregnancy (CSP) is a high-risk ectopic pregnancy, and the influence of surgical treatments on subsequent fertility and pregnancy outcomes remains poorly understood. This study aimed to investigate the impact of dif…

OBJECTIVE: Single-port laparoscopic surgery (SPLS) is an effective, minimally invasive, feasible, and promising surgical technique for the treatment of various benign and malignant gynecological diseases. This study aimed to evaluate the di…

As we all know, female obesity has become a global epidemic, which is usually accompanied with endocrine and metabolic disorders. Obese women are more likely to experience reproductive problems, including infertility, embryonic developmenta…

BACKGROUND: Anti-Müllerian hormone (AMH) is now considered the best serum biomarker of ovarian reserve, while basal sex hormones are classic markers used for assessing ovarian reserve. The interaction between AMH and sex hormones are compli…

To identify a new drug candidate for treating endometriosis which has fewer side effects, a new polymeric nanoparticle gene delivery system consisting of polyethylenimine-grafted chitosan oligosaccharide (CSO-PEI) with hyaluronic acid (HA) …

BACKGROUND: Intravenous leiomyomatosis is a rare, benign, smooth muscle tumor originating in the uterus that may extend through the inferior vena cava into the heart. Intracardiac leiomyomatosis (ICL), present in 10% of patients with intrav…

Objective:To research the serum CA125 levels in patients with endometriosis before and after surgery.Methods:Sixty-two patients with endometriosis who were treated with surgery were selected,the serum CA125 levels before and after surgery w…

Objective To study and improve the diagnosis and treatment of ureteral endometriosis. Methods The clinical data of 8 ureteric endometriosis were retrospectively analyzed. Their mean age was 38 years (range,32～49 years).Of the 8 cases,3 case…

Objective:To explore the reasonably diagnosis and therapeutics of iatrogenic endometriosis,reduce the incidence and recurrence rate.Methods:86 cases of iatrogenic endometriosis were analyzed retrospectively.Results:The 83 cases in all 86 ca…

Objective:To explore the clinical value of ultrasound in diagnosis of adenomyosis.Methods: A total of 120 patients suspected adenomyosis underwent examination of abdominal or Transvaginal ultrasound in preoperative and verified by histopath…

Objective:To explore the relationship of the cancer antigen 125(CA125) with endometriosis.Methods:Serum CA125 was measured by RIA in patients with endometriosis,hysteromyoma and cervix cancer as well as normal controls.Results:The positive …