Lactic acid modification of histones represents an emerging post-translational modification that establishes a critical link between cellular metabolic reprogramming and epigenetic regulation through the covalent binding of lactic acid to h…
Endometriosis (EMs) is a gynecological inflammatory disease that depends on estrogen. Its chief symptoms include dysmenorrhea, chronic pelvic pain, reduced fertility, and pelvic masses. Although various hormonal therapies and surgical treat…
Among gynecologic malignancies, ovarian cancer (OC) stands out as a highly aggressive disease with the highest mortality rate and the poorest prognosis. At the beginning stage, it demonstrates high sensitivity to platinum-based chemotherapy…
BACKGROUND: Ovarian endometriotic cysts (OEC) represent the primary manifestation of endometriosis, constituting a hormonally dependent inflammatory disorder in gynecology. It significantly affects the quality of life and reproductive healt…