Koki Shimura

No ORCID on file · 9 papers in corpus · active 2021-2026

Study types

  • article 7
  • other 2

Condition tags

  • endometriosis 8
  • mesh:D004715 7
  • endometrioma 3
other 2026
Proposed Role of RGS1 in Modulating IL-1β-IL-1R1-IRAK4-TAK1 Signaling in Endometriotic Stromal Cells
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-025-02014-2
other 2025
Daidzein-rich isoflavone aglycones inhibit 17β-hydroxysteroid dehydrogenase 1 and increase estrogen sulfotransferase in endometriosis
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.1080/09513590.2025.2516202

OBJECTIVE: Endometriosis is an estrogen-dependent disease wherein isoflavones interact with estrogen receptors. Daidzein-rich isoflavone aglycones (DRIAs) have been shown to inhibit cell proliferation and aromatase activity in vitro and in …

article 2025
Pathogenesis, Diagnosis, and Management of Inguinal Endometriosis: A Case Series of Six Patients
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-025-01796-9
article 2023
Hepcidin as a key regulator of iron homeostasis triggers inflammatory features in the normal endometrium
Free radical biology & medicine ·doi:10.1016/j.freeradbiomed.2023.10.402

Menstrual blood, containing high iron levels, can undergo retrograde transport into the abdominal cavity. Excess iron causes oxidative stress and inflammation. Iron metabolism is regulated by hepcidin, and serum hepcidin levels are increase…

article 2023
Is neonatal uterine bleeding responsible for early-onset endometriosis?
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-023-01099-1

BACKGROUND: It has been hypothesized that the origin of early-onset endometriosis could be from endometrial mesenchymal stem cells (eMSCs) in neonatal uterine blood (NUB). There is no information on the possible mechanistic basis linking an…

article 2022
Low-Nutrient Environment-Induced Changes in Inflammation, Cell Proliferation, and PGC-1α Expression in Stromal Cells with Ovarian Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-022-01089-5
article 2022
Postoperative Pregnancy Outcomes Following Laparoscopic Surgical Management in Women with Stage III/IV Endometriosis: A Single-Center Follow-Up Study
·doi:10.2139/ssrn.4201389
article 2022
Progesterone Receptor Status of Epithelial Cells as a Predictive Marker for Postoperative Recurrence of Endometriosis
The Journal of clinical endocrinology and metabolism ·doi:10.1210/clinem/dgac118

CONTEXT: Progesterone resistance including progesterone receptor (PR) deficiency contributes to the pathophysiology of endometriosis; however, whether the PR expression levels in ovarian endometrioma (OE) correlate with the postoperative re…

article 2021
Reduced innate lymphoid cells in the endometrium of women with endometriosis
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.13502

PROBLEM: Innate lymphoid cells (ILCs), a recently discovered family of innate immune cells, are responsible for the early immune response, and control both innate and adapted immune system via cytokine secretion. The role of ILCs in endomet…