Xuewen Kang

No ORCID on file · 2 papers in corpus

lab-animal 2025

Therapeutic potential of targeting the IRF2/POSTN/Notch1 axis in nucleus pulposus cells for intervertebral disc degeneration

Journal of neuroinflammation ·doi:10.1186/s12974-025-03335-4

BACKGROUND: Intervertebral disc degeneration (IDD) is a leading cause of low back pain, often linked to inflammation and pyroptosis in nucleus pulposus (NP) cells. The role of Periostin (POSTN) in IDD remains unclear. OBJECTIVE: This study…

review 2023

The Role of S100A6 in Human Diseases: Molecular Mechanisms and Therapeutic Potential

Biomolecules ·doi:10.3390/biom13071139

S100A6, also known as calcyclin, is a low-molecular-weight Ca2+-binding protein from the S100 family that contains two EF-hands. S100A6 is expressed in a variety of mammalian cells and tissues. It is also expressed in lung, colorectal, panc…