Claudia Raperport

review 2026

·doi:10.1111/tog.70037

ABSTRACT Key Content Unexplained infertility accounts for up to 30% of cases of infertility. Potential causes for unexplained infertility have been proposed including reduced oocyte quality, poor endometrial receptivity, ovulatory PCOS, sub…

rct 2025

Progesterone Luteal Support in Natural Cycles for Unexplained Infertility: A Randomised Controlled Trial (The PiNC Trial)

BJOG : an international journal of obstetrics and gynaecology ·doi:10.1111/1471-0528.18171

OBJECTIVE: To compare the effect of luteal-phase progesterone supplementation in natural cycles to expectant management on live birth rates in women with unexplained infertility (UI). DESIGN: An open-label, parallel-arm, single-centre rand…

meta-analysis 2024

Optimizing intrauterine insemination: A systematic review and meta-analysis of the effectiveness and safety of clinical treatment add-ons

Acta obstetricia et gynecologica Scandinavica ·doi:10.1111/aogs.14858

INTRODUCTION: Intrauterine insemination (IUI) is one of the most widespread fertility treatments. However, IUI protocols vary significantly amongst fertility clinics. Various add-on interventions have been proposed to boost success rates. T…

meta-analysis 2023

Endogenous progesterone in unexplained infertility: a systematic review and meta-analysis

Journal of assisted reproduction and genetics ·doi:10.1007/s10815-022-02689-5

PURPOSE: To investigate the possibility that altered actions of endogenous progesterone affect receptivity and contribute to unexplained infertility (UI). METHODS: Two authors electronically searched MEDLINE, CINAHL and Embase databases fr…