Heng-Kien Au

No ORCID on file · 10 papers in corpus
case-report 2024
Women's health reports (New Rochelle, N.Y.) ·doi:10.1089/whr.2024.0074

BACKGROUND: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe dermatological conditions, predominantly affecting women with mortality rates of 4.8-48%. Antibiotics are common triggers. They cause painful mucous …

other 2022
International journal of molecular sciences ·doi:10.3390/ijms232112740

Frequent consumption of diet drinks was associated with oocyte dysmorphism, decreased embryo quality, and an adverse effect on pregnancy rate. We investigated the harmful effects of aspartame and potential mechanisms through which it increa…

observational 2021
PloS one ·doi:10.1371/journal.pone.0257268

PURPOSE: To compare the risk of neurodevelopmental disorders in children conceived via intracytoplasmic sperm injection (ICSI) and those conceived naturally. MATERIALS AND METHODS: A population-based cohort study using data retrieved from …

review 2018
International journal of molecular sciences ·doi:10.3390/ijms19082385

Endometriosis is an estrogen-dependent inflammatory disease that affects up to 10% of women of reproductive age and accounts for up to 50% of female infertility cases. It has been highly associated with poorer outcomes of assisted reproduct…

lab-animal 2015
PloS one ·doi:10.1371/journal.pone.0145256

Transforming growth factor (TGF-β)/TGF-β receptor signal is known to promote cell migration. Up-regulation of TGF-β in serum/peritoneal fluid and increased levels of pluripotent transcription factor OCT4 in endometriotic tissues are frequen…

other 2013
Fertility and sterility ·doi:10.1016/j.fertnstert.2012.11.033

OBJECTIVE: To identify the impact of the pluripotent transcription factor OCT4 in endometrial cell migration and endometriosis. DESIGN: The OCT4 expression and cell migration study. SETTING: Research institution and reproductive medical c…

other 2012
Molecular biology reports ·doi:10.1007/s11033-011-0828-9

Recently, endometrial hyperplasia was identified as presenting a higher risk for progressing to endometrial carcinoma more readily than adenomyosis. The Lcn-2 gene encodes neutrophil gelatinase-associated lipocalin (NGAL), which promotes ce…

review 2005
Reproductive medicine and biology ·doi:10.1111/j.1447-0578.2005.00098.x

The physiological changes in endometriosis involving multiple steps of matrix remodeling include abnormal tissue growth, invasion, and adhesion formation. Endometriosis-associated abnormal matrix remodeling is affected by several molecular …

meta-analysis 2004
Best practice & research. Clinical obstetrics & gynaecology ·doi:10.1016/j.bpobgyn.2004.03.003

Endometriosis is a benign but aggressive disease. It occurs when shed endometrium from the female reproductive tract grows at a site outside the uterus. The physiological changes in endometriosis-abnormal tissue growth, invasion, and adhesi…

observational 2002
Human Reproduction ·doi:10.1093/humrep/17.2.351

BACKGROUND: The occurrence of fluid accumulation within the uterine cavity was examined in women undergoing IVF to investigate its correlation with tubal disease and impact on the pregnancy outcome. METHODS: A registry of ultrasound proced…