Gu M

ORCID: 0009-0001-4642-0217 · 10 papers in corpus
diagnostic-accuracy 2025
Frontiers in medicine ·doi:10.3389/fmed.2025.1720933

OBJECTIVE: Our study aims to establish and validate a diagnostic scoring system for distinguishing malignant cystic ovarian tumors (MCOTs) from benign cystic ovarian tumors (BCOTs). METHODS: The study population was sourced from two indepe…

review 2024
Journal of ovarian research ·doi:10.1186/s13048-024-01448-7

Ovarian fibrosis, characterized by the excessive proliferation of ovarian fibroblasts and the accumulation of extracellular matrix (ECM), serves as one of the primary causes of ovarian dysfunction. Despite the critical role of ovarian fibro…

lab-animal 2023
Journal of ovarian research ·doi:10.1186/s13048-023-01215-0

BACKGROUND: Traditional Chinese medicine has been used for a long time to treat a variety of gynecological diseases. Among various traditional Chinese medicine, Dingkun Pill (DK) has been used for the treatment of female gynecological disea…

lab-animal 2023
Bioorganic & medicinal chemistry letters ·doi:10.1016/j.bmcl.2023.129255

EP2 is a G protein-coupled receptor for prostaglandin E2 (PGE2) derived from cell membrane-released arachidonic acid upon various harmful and injurious stimuli. It is commomly upregulated in tumors and injured brain tissues, as its activati…

rct 2023
Frontiers in endocrinology ·doi:10.3389/fendo.2023.1168175

OBJECTIVE: The aim of this study is to optimize the treatment methods of infertility, which is suggested to be mainly caused by thin endometrium, using a special form of traditional Chinese medicine, the Dingkun pill (DKP), to increase the …

lab-animal 2022
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.2206000119

Estrogen and progesterone specify the establishment of uterine receptivity mainly through their respective nuclear receptors, ER and PR. PR is transcriptionally induced by estrogen-ER signaling in the endometrium, but how the protein homeos…

other 2021
Aging ·doi:10.18632/aging.202347

Pancreatic ductal adenocarcinoma (PDAC) will become the second most common cause of death in North America and Europe over the next 10 years owing to the lack of early diagnosis, poor treatment, and poor prognosis. This study evaluated the …

case-report 2018
Medicine ·doi:10.1097/md.0000000000013506

INTRODUCTION: A choristoma formed by heterotopic tissue rarely occurs in the throat, especially one accompanied with cleft palate in a new-born baby. PATIENT CONCERNS: An 18-month-old female patient was admitted to the hospital for apparen…

lab-animal 2018
Cell death & disease ·doi:10.1038/s41419-017-0197-y

Hormone therapy drugs, such as bicalutamide and enzalutamide, directed against prostate cancer focus on androgen receptor (AR) signaling and are initially effective, but the disease progresses to lethality as resistance to these drugs devel…

other 1999
Zhonghua fu chan ke za zhi

OBJECTIVES: To investigate the pathogenesis of adenomyosis and its immunopathological study after treatment with androgen. METHODS: Estrogen receptor (ER), progestoren receptor (PR), epidermal growth factor receptor (EGFR) and growth hormo…