Ko-Chieh Huang

No ORCID on file · 9 papers in corpus
lab-animal 2025
Bioscience of microbiota, food and health ·doi:10.12938/bmfh.2024-129

Dysmenorrhea, the most prevalent gynecologic complaint among adolescent females, often has unclear underlying causes. However, it is widely recognized that the accumulation of estrogen and prostaglandins mediates inflammatory responses, lea…

rct 2025
Biomedicines ·doi:10.3390/biomedicines13081970

Background: Uterine leiomyomas, commonly known as fibroids, are the most prevalent benign tumors in women of reproductive age and a major contributor to gynecological morbidity. Although surgery and hormonal therapies are standard treatment…

rct 2024
Nutrients ·doi:10.3390/nu16234026

BACKGROUND: Primary dysmenorrhea, a highly prevalent condition that significantly impacts women's daily activities and quality of life, occurs without underlying pelvic pathological changes. Conventional treatments, such as warm water thera…

lab-animal 2024
Redox biology ·doi:10.1016/j.redox.2024.103411

Uterine leiomyoma (UL), commonly referred to as benign tumors, is characterized by excessive cell proliferation, extracellular matrix (ECM) accumulation, and the presence of stem cell-like properties. Nicotinamide adenine dinucleotide (NAD+…

meta-analysis 2023
Nutrients ·doi:10.3390/nu15132830

Dysmenorrhea causes pain and inconvenience during menstruation. In addition to medication, natural compounds are widely used to relieve various types of pain. In this study, we aimed to assess the effects of vitamin D (vit. D) supplementati…

review 2023
Cells ·doi:10.3390/cells12081117

Uterine fibroids (UFs) are the most important benign neoplastic threat to women's health worldwide, with a prevalence of up to 80% in premenopausal women, and can cause heavy menstrual bleeding, pain, and infertility. Progesterone signaling…

lab-animal 2020
Nutrients ·doi:10.3390/nu12103012

Primary dysmenorrhea is a common occurrence in adolescent women and is a type of chronic inflammation. Dysmenorrhea is due to an increase in oxidative stress, which increases cyclooxygenase-2 (COX-2) expression, increases the concentration …

lab-animal 2019
Cancers ·doi:10.3390/cancers11081131

Uterine leiomyomas, also known as fibroids, are common and prevalent in women of reproductive age. In this study, the effect of Isoliquiritigenin (ISL), a licorice flavonoid, on the anti-proliferation of uterine leiomyoma was investigated. …

lab-animal 2019
Journal of pineal research ·doi:10.1111/jpi.12620

The circadian nature of melatonin has a protective effect on the progression of female reproductive cancers, including breast and ovarian cancers. However, the effect of melatonin on the growth of uterine leiomyoma is still unclear. In this…