Bulent Ozpolat

No ORCID on file · 4 papers in corpus
lab-animal 2025
Simvastatin-loaded liposomal nanoparticles as treatment for adenomyosis in a patient-derived xenograft mouse model: a pilot study
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology ·doi:10.1080/01443615.2025.2502083

BACKGROUND: Adenomyosis is a common gynaecological condition where ectopic endometrial glands and stroma grow within the myometrium. This condition has a high clinical burden impacting those afflicted with debilitating symptoms including he…

review 2024
The Role of Nanomedicine in Benign Gynecologic Disorders
Molecules (Basel, Switzerland) ·doi:10.3390/molecules29092095

Nanomedicine has revolutionized drug delivery in the last two decades. Nanoparticles appear to be a promising drug delivery platform in the treatment of various gynecological disorders including uterine leiomyoma, endometriosis, polycystic …

lab-animal 2019
PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis
EBioMedicine ·doi:10.1016/j.ebiom.2018.11.045

BACKGROUND: Inflammatory mediator prostaglandin E2-prostaglandin E2 receptor EP3 (PTGER3) signaling is critical for tumor-associated angiogenesis, tumor growth, and chemoresistance. However, the mechanism underlying these effects in ovarian…

lab-animal 2013
Mullerian inhibiting substance suppresses proliferation and induces apoptosis and autophagy in endometriosis cells in vitro
ISRN obstetrics and gynecology ·doi:10.1155/2013/361489

Objective. To determine the effects of Mullerian inhibiting substance (MIS) treatment on endometriosis cells through study of apoptosis and autophagy. Design. Experimental in vitro study. Setting. University research laboratory. Cell Line. …