Trapphoff T

No ORCID on file · 3 papers in corpus
observational 2024
Scientific reports ·doi:10.1038/s41598-024-60251-y

Smoking of classic cigarettes has been well-established as a health risk factor, including cardiovascular, neurological, and pulmonary diseases. Adverse effects on human reproduction have also been shown. Smokers are assumed to have a signi…

observational 2024
Cells ·doi:10.3390/cells13171497

Expression of the double homeobox 4 (DUX4) transcription factor is highly regulated in early embryogenesis and is subsequently epigenetically silenced. Ectopic expression of DUX4 due to hypomethylation of the D4Z4 repeat array on permissive…

other 2022
Aging ·doi:10.18632/aging.203891

An age-dependent increase in ribosomal DNA (rDNA) methylation has been observed across a broad spectrum of somatic tissues and the male mammalian germline. Bisulfite pyrosequencing (BPS) was used to determine the methylation levels of the r…