STUDY QUESTION: To what extent is male physical activity (PA) associated with fecundability (per-cycle probability of conception)? SUMMARY ANSWER: Preconception levels of vigorous, moderate, or total PA were not consistently associated wit…
ObjectiveTo use self-reported preconception data to derive models that predict the risk of miscarriage.DesignProspective preconception cohort study.SettingNot applicable.PatientsStudy participants were female, aged 21-45 years, residents of…
STUDY QUESTION: To what extent is preconception maternal or paternal coronavirus disease 2019 (COVID-19) vaccination associated with miscarriage incidence? SUMMARY ANSWER: COVID-19 vaccination in either partner at any time before conceptio…
ObjectiveTo assess the effect of randomization to FertilityFriend.com, a mobile computing fertility-tracking app, on fecundability.DesignParallel non-blinded randomized controlled trial nested within the Pregnancy Study Online (PRESTO), a N…
OBJECTIVES: To evaluate the association between preconception contraceptive use and miscarriage. DESIGN: Prospective cohort study. SETTING: Residents of the United States of America or Canada, recruited from 2013 until the end of 2022. P…
ObjectiveTo evaluate the association between seasonal influenza vaccination and miscarriage using data from an ongoing, prospective cohort study.MethodsWe analyzed 2013-2022 data from PRESTO (Pregnancy Study Online), a prospective prepregna…
PURPOSE: To evaluate the relationships among history of asthma, asthma severity, and spontaneous abortion (SAB). METHODS: Pregnancy Study Online is a preconception cohort study of North American couples. During the preconception period, fe…
STUDY QUESTION: Can we derive adequate models to predict the probability of conception among couples actively trying to conceive? SUMMARY ANSWER: Leveraging data collected from female participants in a North American preconception cohort s…
STUDY QUESTION: To what extent is female preconception antibiotic use associated with fecundability? SUMMARY ANSWER: Preconception antibiotic use overall was not appreciably associated with fecundability. WHAT IS KNOWN ALREADY: Antibiotic…