Giles J

No ORCID on file · 7 papers in corpus
observational 2026
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-026-01598-x

BACKGROUND: Despite advancements in imaging techniques, the non-invasive diagnosis of adenomyosis remains particularly challenging due to the overlap of imaging features with other uterine diseases, and the lack of consistent correlation wi…

observational 2024
International journal of molecular sciences ·doi:10.3390/ijms252312600

Previous studies have linked the microbiome of distinct body habitats to obesity and infertility; however, the often-divergent results observed have left the role of the so-called "second genome" in obese infertile patients incompletely exp…

lab-animal 2024
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-023-01182-7

BACKGROUND: Women with adenomyosis are characterized by having defective decidualization, impaired endometrial receptivity and/or embryo-maternal communication, and implantation failure. However, the molecular mechanisms underlying adenomyo…

lab-animal 2022
Journal of personalized medicine ·doi:10.3390/jpm12020219

Adenomyosis is related to infertility and miscarriages, but so far there are no robust in vitro models that reproduce its pathological features to study the molecular mechanisms involved in this disease. Endometrial organoids are in vitro 3…

other 2022
Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2022.12.008

RESEARCH QUESTION: Do extracellular vesicles secreted by the endometrium of women with adenomyosis contain miRNAs involved in adenomyosis-related infertility? DESIGN: A descriptive study using organoids from eutopic endometrium of women wi…

observational 2021
Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2020.12.013

RESEARCH QUESTION: How does the number of oocytes used affect the cumulative live birth rate (CLBR) in endometriosis patients who had their oocytes vitrified for fertility preservation? DESIGN: Retrospective observational study including d…

observational 2020
Fertility and sterility ·doi:10.1016/j.fertnstert.2019.11.017

OBJECTIVE: To describe the outcome of fertility preservation (FP) using vitrified oocytes in patients with endometriosis and to determine the impact of ovarian surgery. DESIGN: Retrospective observational study. SETTING: University-affili…