Holly A Ingraham

No ORCID on file · 2 papers in corpus
lab-animal 2011
Journal of medicinal chemistry ·doi:10.1021/jm1014296

The crystal structure of LRH-1 ligand binding domain bound to our previously reported agonist 3-(E-oct-4-en-4-yl)-1-phenylamino-2-phenyl-cis-bicyclo[3.3.0]oct-2-ene 5 is described. Two new classes of agonists in which the bridgehead anilino…

lab-animal 2009
Cancer research ·doi:10.1158/0008-5472.CAN-08-1622

Estrogens and selective estrogen receptor (ER) modulators such as tamoxifen are known to increase uterine cell proliferation. Mounting evidence suggests that estrogen signaling is mediated not only by ERalpha and ERbeta nuclear receptors, b…