James P. Torres-Pirela

2026

Peroxisome proliferator-activated receptor γ partially regulates the beneficial effects of voluntary wheel exercise in a rat animal model of endometriosis

·doi:10.1177/22840265261497323

Introduction: Voluntary physical activity reduces lesion development and inflammatory parameters in experimental endometriosis, though the mechanisms remain unclear. Peroxisome proliferator-activated receptor γ (PPAR-γ), a regulator of infl…

lab-animal 2024

Impact of exercise on uncoupling protein 1 and macrophage phenotype in mesenteric adipose tissue in an animal model of endometriosis

·doi:10.1152/physiol.2024.39.s1.974

Endometriosis is a gynecological disorder characterized by growth of endometrial tissue outside the uterine cavity, with symptoms which may include chronic pelvic pain and infertility resulting in a decreased quality of life. Previous studi…

lab-animal 2024

Implication of the enteric glia in the IBS-like colonic inflammation associated with endometriosis

BMC women's health ·doi:10.1186/s12905-024-03480-7

BACKGROUND: Endometriosis is a complex gynecological disorder characterized by the ectopic growth of endometrial tissue. Symptoms of endometriosis are known to impair the quality of life of patients, and among these are found dysmenorrhea, …