Haitang He

No ORCID on file · 9 papers in corpus · active 2017-2025

Study types

  • article 8
  • other 1

Condition tags

  • endometriosis 9
  • mesh:D004715 7
article 2025
Estradiol Promotes Endometriosis Progression Via the ERβ/QKI /circSMAD2 Axis
Current pharmaceutical biotechnology ·doi:10.2174/0113892010331129250216041033

AIMS: The present study aimed to examine the roles of circRNA-circSMAD2 and its regulatory mechanisms in endometriosis (EMs). BACKGROUND: Evidence has confirmed that circRNAs play multiple roles in regulating the occurrence and development …

article 2024
CircFOXO3 mediates hypoxia‐induced autophagy of endometrial stromal cells in endometriosis
FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fj.202301654rr

Endometriosis is a benign gynecological disease that shares some common features of malignancy. Autophagy plays vital roles in endometriosis and influences endometrial cell metastasis, and hypoxia was identified as the initiator of this pat…

article 2021
Upregulation of the long noncoding RNA UBOX5 antisense RNA 1 (UBOX5-AS1) under hypoxic conditions promotes epithelial-mesenchymal transition in endometriosis
Annals of translational medicine ·doi:10.21037/atm-20-4546

Background: Endometriosis is a debilitating gynecological condition that manifests many common malignant features, including migration and invasion. Hypoxia is a hallmark of endometriosis, characterized by endometrial cell metastasis via ep…

article 2020
Estrogen-decreased hsa_circ_0001649 promotes stromal cell invasion in endometriosis
Reproduction (Cambridge, England) ·doi:10.1530/rep-19-0540

Endometriosis (EMs) is an estrogen (E2)-dependent inflammatory disorder. Although EMs is considered a benign disease, it presents with malignant characteristics, such as migration and invasion. An increasing number of studies have shown tha…

article 2019
E2‐mediated EMT by activation of β‐catenin/Snail signalling during the development of ovarian endometriosis
Journal of cellular and molecular medicine ·doi:10.1111/jcmm.14668

Endometriosis is an oestrogen-dependent disease, and epithelial-mesenchymal transition (EMT) is involved in the process of endometriosis. Whether oestrogen could induce EMT in endometriosis remains largely unknown. Here, we reported that up…

article 2018
Autophagy contributes to hypoxia-induced epithelial to mesenchymal transition of endometrial epithelial cells in endometriosis†
Biology of reproduction ·doi:10.1093/biolre/ioy128

Endometriosis is a benign gynecologic disorder, and presents with malignant characteristics, such as migration and invasion. Hypoxia has been implicated in triggering epithelial-mesenchymal transition (EMT). Hypoxia is also known to induce …

article 2018
Estradiol promotes EMT in endometriosis via MALAT1/miR200s sponge function
Reproduction (Cambridge, England) ·doi:10.1530/rep-18-0424

Endometriosis is an estrogen-dependent benign gynecological disease that shares some common features of malignancy. Epithelial-mesenchymal transition (EMT) has been recognized as a core mechanism of endometriosis. MALAT1 is widely known as …

other 2017
Estrogen stabilizes hypoxia-inducible factor 1α through G protein-coupled estrogen receptor 1 in eutopic endometrium of endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2016.11.008

OBJECTIVE: To investigate whether G protein-coupled estrogen receptor (GPER, also known as GPR30 and GPER1) stabilizes hypoxia-inducible factor 1α (HIF-1α) in eutopic endometrium (EuEM) of endometriosis. DESIGN: Immunohistochemical analysi…

article 2017
Hypoxia-inducible factor-1α promotes endometrial stromal cells migration and invasion by upregulating autophagy in endometriosis
Reproduction (Cambridge, England) ·doi:10.1530/rep-16-0643

Endometriosis is a benign gynecological disease that shares some characteristics with malignancy like migration and invasion. It has been reported that both hypoxia-inducible factor-1α (HIF-1α) and autophagy were upregulated in ectopic endo…