Larry L. Needham

No ORCID on file · 8 papers in corpus
observational 2010
Environmental health perspectives ·doi:10.1289/ehp.0901091

BACKGROUND: Phthalates, ubiquitous environmental pollutants that may disturb the endocrine system, are used primarily as plasticizers of polyvinyl chloride and as additives in consumer and personal care products. OBJECTIVES: In this study,…

observational 2008
Environmental health perspectives ·doi:10.1289/ehp.10399

BACKGROUND: Environmental toxicants are allegedly involved in decreasing semen quality in recent decades; however, definitive proof is not yet available. In 1976 an accident exposed residents in Seveso, Italy, to 2,3,7,8-tetrachlorodibenzo-…

observational 2008
Chemosphere ·doi:10.1016/j.chemosphere.2008.10.005

Endometriosis among women of reproductive age can result in pain and infertility. The objectives of this study were to test if there is a relation between endometriosis and serum dioxin concentrations as expressed by total toxic equivalence…

observational 2007
Molecular human reproduction ·doi:10.1093/molehr/gam018

Exposure to dioxins and polychlorinated biphenyls (PCBs) has been suggested as a possible etiologic factor for endometriosis, but the association remains highly controversial. To assess whether cytochrome P450 (CYP) gene polymorphisms modul…

2005
·doi:10.1093/aje/161.supplement_1.s30
observational 2005
Environmental research ·doi:10.1016/j.envres.2005.04.003

Endocrine-disrupting chemicals (EDCs) have been proposed as risk factors for endometriosis. Persistent organochlorine compounds, a group of suspected EDCs, are present to some extent in almost all human adipose tissue and blood via the food…

observational 2002
Environmental health perspectives ·doi:10.1289/ehp.02110629

Dioxin, a ubiquitous contaminant of industrial combustion processes including medical waste incineration, has been implicated in the etiology of endometriosis in animals. We sought to determine whether dioxin exposure is associated with end…

2002