A. Germeyer

Background: Endometriosis is a common chronic gynecological disease associated with pain, impaired quality of life, reduced productivity, impaired fertility, and high healthcare costs. Diagnosis is often delayed because symptoms are normali…

Abstract Study question Are there differences at the molecular level in the most important genes of the mTOR/Akt-pathway in granulosa cells (GCs) of patients with or without endometriosis? Summary answer Our data show increased gene express…

Abstract Study question Can the endometrial proteomic signature be used as a minimally invasive biomarker to detect peritoneal endometriosis in women with dysmenorrhea? Summary answer Eutopic endometrial tissue from patients with peritoneal…

BACKGROUND: The pathogenesis of deep infiltrating endometriosis (DIE) is poorly understood. It is considered a benign disease but has histologic features of malignancy, such as local invasion or gene mutations. Moreover, it is not clear whe…

PURPOSE: To study if ovarian response is affected by the type of disease if fertility preservation is required. METHODS: A registry of the trinational fertility preservation network FertiPROTEKT including 992 patients aged 18-40 years unde…

Study question: To compare the pregnancy rate in patients submitted to FET (Frozen Embryos Transfer) of cleavage stage embryos (Group 1), or at the blastocyst stage (Group 2). Summary answer: Our data showed that the transfer of frozen blas…

The human oviduct serves as a conduit for spermatozoa in the peri-ovulatory phase and nurtures and facilitates transport of the developing embryo for nidation during the luteal phase. Interactions between the embryo and oviductal epithelial…

Endometriosis is clinically associated with pelvic pain and infertility, with implantation failure strongly suggested as an underlying cause for the observed infertility. Eutopic endometrium of women with endometriosis provides a unique exp…