Shaohua Ling

No ORCID on file · 3 papers in corpus
observational 2025
Association between mitochondrial SIRTs (SIRT3, SIRT4, and SIRT5) and PCOS
European journal of medical research ·doi:10.1186/s40001-025-02862-3

Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder with unclear pathogenesis. Increasing evidence suggests that oxidative stress and mitochondrial dysfunction contribute to PCOS development. Sirtuins (SIRTs), esp…

other 2025
Identification of EPHB4 as a potential causal gene and therapeutic target for endometriosis using Mendelian randomization
Hereditas ·doi:10.1186/s41065-025-00457-w

OBJECTIVES: Endometriosis is a common condition among women, characterized by chronic pain and infertility, presenting significant challenges for clinicians. This study aims to identify potential druggable targets to offer new therapeutic a…

other 2025
WISP2/CCN5 revealed as a potential diagnostic biomarker for endometriosis based on machine learning and single-cell transcriptomic analysis
Functional & integrative genomics ·doi:10.1007/s10142-025-01631-z

OBJECTIVE: Endometriosis is a prevalent gynecological disease characterized by the ectopic growth of functional endometrial tissue outside the uterine cavity, affecting millions of women worldwide. Currently, the definitive diagnosis relies…