Asada H

No ORCID on file · 12 papers in corpus
lab-animal 2017
Biochimica et biophysica acta. Molecular and cell biology of lipids ·doi:10.1016/j.bbalip.2017.10.002

Endometriosis is a disease characterized by regurgitated lesions which are invasive and migratory, embedding at ectopic, extra-uterine locations. Extracellular glucosylceramides (GlcCers), bioactive sphingolipids potentiating signals for ce…

other 2017
Reproductive medicine and biology ·doi:10.1002/rmb2.12030

AIM: Although a thin endometrium has been well recognized as a critical factor in implantation failure, little information is available regarding the molecular mechanisms. The present study investigated these mechanisms by using genome-wide…

other 2017
Acta obstetricia et gynecologica Scandinavica ·doi:10.1111/aogs.13179

INTRODUCTION: Although endometriosis is a benign disease, it shares some features with cancers, such as invasiveness and the potential to metastasize. This study sought to investigate the epithelial-mesenchymal transition status in human en…

lab-animal 2015
Journal of ovarian research ·doi:10.1186/s13048-015-0179-6

BACKGROUND: Despite endometriosis is common estrogen dependent disease afflicting women in reproductive age, the pathogenesis has not been fully elucidated. Retinoic acid has various functions in cells as biologic modulator, and aberrant re…

observational 2013
Endocrine journal ·doi:10.1507/endocrj.ej13-0027

Nerve growth factor (NGF) has been recently proposed as one of the key factors responsible not only for promotion of nerve fiber growth but also for the onset and maintenance of pain in a variety of diseases. The aim of this study was to in…

other 2011
Journal of ovarian research ·doi:10.1186/1757-2215-4-2

BACKGROUND: Blood flow in the corpus luteum (CL) is closely related to luteal function. It is unclear how luteal blood flow is regulated. Standardized ovarian-stimulation protocol with a gonadotropin-releasing hormone agonist (GnRHa long pr…

observational 2010
Human Reproduction ·doi:10.1093/humrep/deq222

BACKGROUND: The relationship between fibroids and infertility remains an unsolved question, and management of intramural fibroids is controversial. During the implantation phase, uterine peristalsis is dramatically reduced, which is thought…

lab-animal 2010
PloS one ·doi:10.1371/journal.pone.0010387

BACKGROUND: The human endometrium undergoes cyclical regeneration throughout a woman's reproductive life. Ectopic implantation of endometrial cells through retrograde menstruation gives rise to endometriotic lesions which affect approximate…

observational 2009
Fertility and sterility ·doi:10.1016/j.fertnstert.2009.04.041

A cross-sectional comparative study among women who underwent surgical treatment for endometriosis revealed that frequency of the Ala/Ala genotype at aryl hydrocarbon receptor repressor (AHRR) Pro185Ala polymorphism was three times higher (…

nonrandomized-trial 2009
Journal of ovarian research ·doi:10.1186/1757-2215-2-1

BACKGROUND: Blood flow in the corpus luteum (CL) is associated with luteal function. The present study was undertaken to investigate whether luteal function can be improved by increasing CL blood flow in women with luteal phase defect (LFD)…

lab-animal 2007
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.0704472104

Over the course of pregnancy, the human uterus undergoes a 500- to 1,000-fold increase in volume and a 24-fold increase in weight. The uterine smooth muscle layer or myometrium is remodeled, and both cell hypertrophy and hyperplasia are evi…

review 2005
Reproductive medicine and biology ·doi:10.1111/j.1447-0578.2005.00101.x

Acetylation of histones is cooperatively regulated by two groups of enzymes, histone acetyltransferases and histone deacetylases. Histone acetylation status plays a fundamental role in the level of gene transcription; numerous studies have …