Joshi N

Endometriosis is a chronic systemic disease affecting ∼10-15% of women of reproductive age, often resulting in chronic pelvic pain and infertility. Despite its high prevalence, diagnosis is frequently delayed. tRNA-derived fragments (tRFs) …

Endometriosis is an inflammatory chronic gynecological condition that affects 10-15% of reproductive-age women which causes pelvic pain and infertility. The disease is characterized by the growth of endometrial tissue outside the uterine ca…

In brief: Although endometriosis is known to be a debilitating gynecological disease associated with chronic pelvic pain and infertility, our understanding of its molecular underpinnings is incomplete. Using experimentally induced nonhuman …

IN BRIEF: The HIPPO signaling effectors YAP1 and WWTR1 are required for murine pregnancy initiation, and mutation of these factors compromises the decidualization response and overall pregnancy success. ABSTRACT: Endometrial stromal cell d…

Endometrial cancer (EC), endometriosis (ENDO), and obesity (OBY) are interconnected conditions in women that may share underlying genetic pathways. This study aimed to identify shared genetic pathways and differential gene expressions acros…

Endometrial stromal cell decidualization is required for pregnancy success. Although this process is integral to fertility, many of the intricate molecular mechanisms contributing to decidualization remain undefined. One pathway that has be…

Abstract Female infertility is a complex disease linked to multiple etiologies including genetic factors. Owing to the multifactorial nature of infertility, it is often difficult to identify single causative genes. Despite this challenge, i…

OBJECTIVE: To explore disparities in prematurity and low birth weight (LBW) by maternal race and ethnicity among singletons conceived with and without assisted reproductive technology (ART). METHODS: We performed a retrospective cohort stu…

OBJECTIVE: To study follicular microenvironment in terms of free radical dynamics, oocyte quality, and assisted reproductive technology (ART) outcomes among women with (group A) and without (group B) endometriosis. DESIGN: Prospective coho…

OBJECTIVE: To estimate trends in good perinatal outcomes (singleton live births at term with birthweight more than 2,500 g) among live births after assisted reproductive technology in the United States from 2000 to 2008, and associated fact…