Lynda Uphouse — Endo Lab

lab-animal 2020

Progesterone and Allopregnanolone Rapidly Attenuate Estrogen-Associated Mechanical Allodynia in Rats with Persistent Temporomandibular Joint Inflammation

Frontiers in integrative neuroscience ·doi:10.3389/fnint.2020.00026

Temporomandibular joint disorder (TMD) is associated with pain in the joint (temporomandibular joint, TMJ) and muscles involved in mastication. TMD pain dissipates following menopause but returns in some women undergoing estrogen replacemen…

lab-animal 2011

Mechanisms responsible for progesterone's protection against lordosis-inhibiting effects of restraint II. Role of progesterone metabolites

Hormones and behavior ·doi:10.1016/j.yhbeh.2011.05.005

When ovariectomized Fischer female rats are hormonally primed with 10 μg estradiol benzoate, a 5 min restraint experience rapidly inhibits lordosis behavior. Addition of progesterone to the hormonal priming prevents this restraint-induced i…

lab-animal 2004

Estrogen and progesterone dose-dependently reduce disruptive effects of restraint on lordosis behavior

Hormones and behavior ·doi:10.1016/j.yhbeh.2003.10.001

Ovariectomized rats were hormonally primed with various doses of estradiol benzoate (EB; 0.5-10 microg) in combination with various doses of progesterone (2.5-500 microg) to induce sexual receptivity. Females were then subjected to 5 min re…

lab-animal 2002

Strain differences in the response to the 5-HT1A receptor agonist, 8-OH-DPAT

Pharmacology, biochemistry, and behavior ·doi:10.1016/s0091-3057(02)00714-1

Fischer and Sprague-Dawley ovariectomized rats were hormonally primed with estradiol benzoate (EB) and progesterone, and the ability of the 5-HT(1A) receptor agonist, (+/-) 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT), to inhibit lord…

lab-animal 1999

5-HT2C receptor involvement in female rat lordosis behavior

Brain research ·doi:10.1016/s0006-8993(99)01159-2

Adult, hormone-primed, ovariectomized rats (CDF-344) with bilateral implants within the ventromedial nucleus of the hypothalamus (VMN), were injected with 0.5 microgram estradiol benzoate followed 48 h later with 500 microgram progesterone.…