M.O. Pulkkinen

No ORCID on file · 13 papers in corpus
nonrandomized-trial 1995
Acta obstetricia et gynecologica Scandinavica ·doi:10.3109/00016349509024388

BACKGROUND: To measure the effect of oral naproxen and nimesulide treatments on the uterine and ovarian arterial blood flow velocity in both eumenorrheic and dysmenorrheic women. METHODS: The double-blind, placebo-controlled, study compris…

nonrandomized-trial 1992
Acta obstetricia et gynecologica Scandinavica ·doi:10.3109/00016349209009915

To study the effects of non-steroidal anti-inflammatory drugs (NSAIDs) on uterine contractility in different parts of the uterus and on the direction and velocity of propagation of the activity, intra-uterine pressure (IUP) was measured sim…

other 1991
Biopharmaceutics & drug disposition ·doi:10.1002/bdd.2510120204

Nimesulide is a non-steroidal anti-inflammatory agent which has proved to be effective in reducing menstrual discomfort in dysmenorrhoeaic women. To determine the concentrations of this drug in the uterus (fundus, cervix), oviduct, and ovar…

rct 1987
Journal of clinical pharmacology ·doi:10.1177/009127008702700110

A double-blind crossover study was carried out to evaluate the therapeutic efficacy of nimesulide and its effects on uterine activity, menstrual fluid prostaglandin F, and pain in women suffering from primary dysmenorrhea. Twenty-three wome…

other 1980
Acta obstetricia et gynecologica Scandinavica ·doi:10.3109/00016348009154095
nonrandomized-trial 1979
·doi:10.1016/s0090-6980(79)80064-7

To extend observations in 11 weeks pregnant patients the mechanism of prostaglandin (PG) action has been examined in 6 weeks pregnant women (LMP). In 10 gravidas menstrual induction was attempted with a single slow release vaginal supposito…

nonrandomized-trial 1978
Prostaglandins ·doi:10.1016/0090-6980(78)90048-5

In 12 dysmenorrheic patients we examined the therapeutic action of the Prostaglandin-synthesis inhibitor: Ibuprofen, a non-steroidal analgesic agent. Ibuprofen highly significantly reduced the resting pressure (P less than 0.001), active pr…

rct 1978
Prostaglandins ·doi:10.1016/0090-6980(78)90138-7
nonrandomized-trial 1977
Acta obstetricia et gynecologica Scandinavica ·doi:10.3109/00016347709158344
nonrandomized-trial 1977
Prostaglandins ·doi:10.1016/0090-6980(77)90056-9

The Prostaglandin-synthesis inhibitor: Naproxen-Sodium (NS) (an analgesic agent) very significantly (P less than 0.001) reduced the "resting" and "active" pressures and the frequency of cyclic uterine activity of 10 dysmenorrheic patients. …

nonrandomized-trial 1975
Prostaglandins ·doi:10.1016/0090-6980(75)90068-4
other 1973
American journal of obstetrics and gynecology ·doi:10.1016/0002-9378(73)90517-6
other 1973
Prostaglandins ·doi:10.1016/0090-6980(73)90030-0