Schrepf AD

No ORCID on file · 3 papers in corpus
observational 2023
Neurobiology and long-term impact of bladder-filling pain in humans: a Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) research network study
Pain ·doi:10.1097/j.pain.0000000000002944

Pain with bladder filling remains an unexplained clinical presentation with limited treatment options. Here, we aim to establish the clinical significance of bladder filling pain using a standardized test and the associated neural signature…

lab-animal 2023
Neurotrophins and Their Receptors, Novel Therapeutic Targets for Pelvic Pain in Endometriosis, Are Coordinately Regulated by IL-1β via the JNK Signaling Pathway
The American Journal of Pathology ·doi:10.1016/j.ajpath.2023.04.007

Pelvic pain in women with endometriosis is attributed to neuroinflammation and afferent nociceptor nerves in ectopic and eutopic endometrium. The hypothesis that uterine nociception is activated by IL-1β, a prominent cytokine in endometrios…

observational 2021
Incidence and predictors of persistent pelvic pain following hysterectomy in women with chronic pelvic pain
American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2021.08.038

BACKGROUND: Chronic pelvic pain is a debilitating problem that afflicts 15% to 20% of women in the United States. Although more than 200,000 hysterectomies are performed annually for the treatment of chronic pelvic pain, previous studies in…