Fernand Labrie

No ORCID on file · 4 papers in corpus
lab-animal 2007
Temporal analysis of E2 transcriptional induction of PTP and MKP and downregulation of IGF-I pathway key components in the mouse uterus
Physiological genomics ·doi:10.1152/physiolgenomics.00291.2005

17beta-Estradiol (E2) is well known to be associated with uterine cancer, endometriosis, and leiomyomas. Although insulin-like growth factor I (IGF-I) has been identified as a mediator of the uterotrophic effect of E2 in several studies, th…

other 2006
Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity
Protein science : a publication of the Protein Society ·doi:10.1110/ps.051905906

Androgens exert their effects by binding to the highly specific androgen receptor (AR). In addition to natural potent androgens, AR binds a variety of synthetic agonist or antagonist molecules with different affinities. To identify molecula…

other 2006
Pharmaceutical compositions and uses for androst-5-ene-3 beta,17 beta-diol

Androst-5-ene-3 beta ,17 beta diol is used to treat or reduce the likelihood of acquiring osteoporosis or menopausal symptoms, or other diseases affected by estrogen receptor activity, like vaginal atrophy, hyporgonadism, diminished libido,…

nonrandomized-trial 1990
Hormonal and biochemical changes during treatment of endometriosis with the luteinizing hormone-releasing hormone (LH-RH) agonist [D-Trp6,des-Gly-NH2(10)]LH-RH ethylamide
Fertility and sterility ·doi:10.1016/s0015-0282(16)53694-2

The effect of medical oophorectomy induced by treatment with the luteinizing hormone-releasing hormone (LH-RH) agonist [D-Trp6,des-Gly-NH2(10)]LH-RH ethylamide was studied in 34 patients with laparoscopically proven endometriosis. Tamoxifen…