M A Boric — Endo Lab

lab-animal 2015

Differential expression of upstream stimulatory factor (USF) 2 variants in eutopic endometria from women with endometriosis: estradiol regulation

Biological research ·doi:10.1186/s40659-015-0047-2

BACKGROUND: Endometriosis, pro-inflammatory and invasive benign disease estrogen dependent, abnormally express in endometria the enzyme P450Arom, positively regulated by steroid factor-1 (SF-1). Our objective was to study the nuclear protei…

observational 2015

Nerve Fibres Detection in Paired Eutopic and Ectopic Endometria from Women with Endometriosis: Correlation with Nerve Growth Factor Expression

·doi:10.4236/ojog.2015.57060

Endometriosis, disorder characterized by the presence of endometrium outside the uterus cavity, is associated with chronic pelvic pain. Nerve growth factor (NGF) participates in development, repair and survival of neurons. We evaluated NGF …

2013

TNF system in eutopic endometrium from women with endometriosis

·doi:10.4236/ojog.2013.32051

The role of the tumor necrosis factor (TNF) system in endometriosis is not completely clear and therefore was the focus of this study. In eutopic endometria obtained from women with (n = 41) and without (controls; n = 34) endometriosis duri…

lab-animal 2010

P450Arom induction in isolated control endometrial cells by peritoneal fluid from women with endometriosis

Fertility and sterility ·doi:10.1016/j.fertnstert.2010.03.036

OBJECTIVE: To study the effect of peritoneal fluid from women with (PF-E) and without (PF-C) endometriosis on P(450)Arom expression in endometrial cells. DESIGN: Experimental study. SETTING: University research unit. PATIENT(S): Forty wo…

lab-animal 2009

Association between MMP1 and MMP9 activities and ICAM1 cleavage induced by tumor necrosis factor in stromal cell cultures from eutopic endometria of women with endometriosis

·doi:10.1530/rep-09-0196

Abstract Endometriosis is a benign gynecological pathology in which immune system deregulation may play a role in its initiation and progression. In endometriotic lesions, intercellular adhesion molecule-1 (ICAM1) is released from the cell …

lab-animal 2009

Association between MMP1 and MMP9 activities and ICAM1 cleavage induced by tumor necrosis factor in stromal cell cultures from eutopic endometria of women with endometriosis

Reproduction (Cambridge, England) ·doi:10.1530/REP-09-0196

Endometriosis is a benign gynecological pathology in which immune system deregulation may play a role in its initiation and progression. In endometriotic lesions, intercellular adhesion molecule-1 (ICAM1) is released from the cell membrane …

observational 2009

Nuclear factor kappaB pathway and interleukin-6 are affected in eutopic endometrium of women with endometriosis

Reproduction (Cambridge, England) ·doi:10.1530/rep-08-0407

In order to investigate the role of the nuclear factor kappaB (NFKB) pathway on gene expression in the eutopic endometrium in endometriosis, and in particular of interleukin-6 (IL6), we evaluated RELA, IkappaB kinase (CHUK), NFKBIA and IL6 …

lab-animal 2009

Peritoneal Fluid Obtained from Women with Endometriosis Induces CYP19A1 Expression in Isolated Control Endometrial Cells.

·doi:10.1093/biolreprod/81.s1.368

Endometriosis patients commonly present altered volume and composition of peritoneal fluid (PF) and also, an endometrial estrogenic micro-environment as consequence of anomalous CYP19A1 expression. This gene is positively regulated by NR5A1…

other 2005

Augmented cell survival in eutopic endometrium from women with endometriosis: expression of c-myc, TGF-beta1 and bax genes

Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-3-45

BACKGROUND: Endometriosis is a common gynaecological disorder characterized by the presence of endometrial tissue outside of the uterus. The fragments in normal menstruation are composed of necrotic and living cells, which do not survive in…