Jianlei Wu

No ORCID on file · 4 papers in corpus
observational 2024
Polymorphisms in miR-17-92 cluster promoter region is associated with risk and prognosis of endometrial cancer
Medicine ·doi:10.1097/md.0000000000039326

Accumulating researches have reported that miR-17-92 cluster expression has strong association with tumorigenesis. In this study, we investigated the effects of 2 genetic polymorphisms in the promoter region of the miR-17-92 cluster and the…

other 2022
Hypermethylation of the GRHL2 promoter region is associated with ovarian endometriosis
Reproduction (Cambridge, England) ·doi:10.1530/rep-21-0383

Abnormal gene expression caused by epigenetic changes, including DNA methylation, is associated with the development and progression of endometriosis. Grainyhead-like 2 gene (GRHL2), a suppressor of epithelial-mesenchymal transition, has be…

observational 2021
Genetic Variation of Glutathione S-Transferase M1 Is Associated with Patients with Ovarian Endometriosis and Endometriosis-Related Primary Infertility
Public health genomics ·doi:10.1159/000517266

BACKGROUND: The aim of the study was to investigate the role of the genetic variation of glutathione S-transferase M1 (GSTM1) in the development of ovarian endometriosis and endometriosis-related primary infertility risk. METHODS: This cas…

other 2021
Identification of Key Differentially Methylated/Expressed Genes and Pathways for Ovarian Endometriosis by Bioinformatics Analysis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-021-00751-8

The goal of this study was to identify genes that were differentially methylated and differentially expressed and their related signaling pathways in ovarian endometriosis tissue. First, the DNA methylation and gene expression profiles in t…