Jacques Mailloux

No ORCID on file · 6 papers in corpus
lab-animal 2012
Macrophage migration inhibitory factor is involved in a positive feedback loop increasing aromatase expression in endometriosis
The American Journal of Pathology ·doi:10.1016/j.ajpath.2012.05.018

Immune-endocrine interplay may play a major role in the pathogenesis of endometriosis. In the present study, we have investigated the interaction between macrophage migration inhibitory factor (MIF), a major pro-inflammatory and growth-prom…

lab-animal 2012
Soluble human IL-1 receptor type 2 inhibits ectopic endometrial tissue implantation and growth: identification of a novel potential target for endometriosis treatment
The American Journal of Pathology ·doi:10.1016/j.ajpath.2012.06.022

Endometriosis is often associated with a chronic pelvic immuno-inflammatory process, which is closely related to disease pathogenesis and major symptoms. Our studies led to the detection of a marked imbalance between IL-1 and its natural in…

observational 2011
Distinct expression of the soluble and the membrane-bound forms of interleukin-1 receptor accessory protein in the endometrium of women with endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2010.12.056

OBJECTIVE: To investigate interleukin (IL) 1 receptor accessory protein (IL1RAcP) expression in the eutopic endometrium of women with endometriosis. DESIGN: Retrospective study. SETTING: Human reproduction research laboratory. PATIENT(S)…

2008
Induction of cyclooxygenase-2 expression and prostaglandin E2 secretion by macrophage migration inhibitory factor in ectopic endometrial cells: role in the pathophysiology of endometriosis
·doi:10.1016/j.fertnstert.2008.07.943
other 2006
Increased expression of matrix metalloproteinase-9 in the eutopic endometrial tissue of women with endometriosis
Human Reproduction ·doi:10.1093/humrep/del297

BACKGROUND: Endometriosis is a disease where endometrial tissue implants in ectopic locations. Remodelling of the extracellular matrix (ECM) is a prerequisite for the implantation of this tissue to be possible. METHODS: In this study, we d…

observational 2003
Deficient expression of tumor necrosis factor receptor type 2 in the endometrium of women with endometriosis
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1034/j.1600-0897.2003.00058.x

PROBLEM: Tumor necrosis factor-alpha (TNF-alpha) is secreted mainly during the menstrual phase and has been suggested to play a role in induction of apoptosis in endometrial cells and menstrual shedding. TNF-alpha receptor type 2 (TNF-RII) …