S Nozawa
No ORCID on file
· 23 papers in corpus
lab-animal
2017
Endometriosis is estrogen-dependent disease that is related to the inflammatory process in the peritoneal cavity. To being activated by pro-inflammatory cytokines, endometriosis is also influenced by the response of progesterone receptors. …
diagnostic-accuracy
2005
A new efficient screening for ovarian cancer based on a combination of two tumor markers, CA602 and CA546, is reported. These two tumor markers can be detected by a combination immunoenzymometric assay of these two antigens. This combinatio…
review
2001
observational
1999
OBJECTIVE: Ovarian clear cell carcinoma is commonly associated with pelvic endometriosis. We retrospectively evaluated clinicopathological data on the association between ovarian clear cell carcinoma and pelvic endometriosis. METHODS: Betw…
diagnostic-accuracy
1998
In this study clinical studies were conducted on galactosyltransferase associated with tumour (GAT) as a newly developed marker of ovarian cancers. The positive rates of GAT with a cut-off value of 16 U/ml (which corresponds to the mean + 2…
lab-animal
1998
OBJECTIVE: Dienogest, a synthetic steroid with progestational activity, is used as a component of oral contraceptives and is currently being evaluated clinically for the treatment of endometriosis. The present study was conducted to confirm…
lab-animal
1997
Dienogest is an orally active synthetic steroid that is used for contraception and is currently being studied for the possible treatment of endometriosis. Earlier we demonstrated that dienogest had therapeutic effects on experimental endome…
lab-animal
1997
BACKGROUND: Dienogest is a synthetic progestational steroid that is used for contraception. It is being studied for the treatment of endometriosis, but its anticancer activity remains unknown. The authors investigated the anticancer effect …
lab-animal
1996
PROBLEM: To determine the effect of estrogen deficiency on populations of immune cells in rats with autotransplanted endometrium. METHOD OF STUDY: Autologous endometrial segments were implanted in the peritoneum of rats. Leukocyte subsets …
1995
lab-animal
1995
PROBLEM: This study examines immune cell populations in rats with autotransplanted endometrium and determines the effect of danazol on leukocyte subsets. METHODS: As an experimental model of endometriosis, an autologous endometrial segment…
diagnostic-accuracy
1994
We examined GAT, a newly developed tumor marker, in serum samples collected from 1,503 females in six institutions: 387 healthy females, 1,052 patients with gynecological diseases including 311 ovarian cancers, and 64 with nongynecological …
nonrandomized-trial
1994
Serum samples from patients with benign or malignant diseases were measured for the newly developed tumor markers CA54/61 and CA602 with the respective EIA kits for assessment of their utility as tumor markers. A total of 5236 patients were…
lab-animal
1994
OBJECTIVE: To establish an experimental system useful for long-term evaluation of human endometrial tissue by its heterotransplantation to SCID mice. METHODS: Human endometrium was transplanted subcutaneously into SCID mice, nude mice, or …
other
1993
observational
1993
OBJECTIVE: To evaluate cell-mediated immunity in endometriosis. DESIGN: Peritoneal fluid and peripheral blood samples from 19 women with macroscopic evidence of endometriosis and 26 controls were submitted to 2-color flow cytometric analys…
other
1993
Galactosyltransferase Associated with Tumor (GAT) was clinically studied in cases of ovarian cancer. When two cut-off levels of GAT were compared, the cut-off level of 16 U/ml (which corresponds to mean + 2SD among healthy females) was foun…
observational
1992
Tumor DNA content (ploidy) was determined by flow-cytometry (FCM) on tissue from 32 epithelial ovarian cancer patients. Staining for DNA analysis was achieved with Propidium Iodide. Peripheral blood lymphocytes were used as reference diploi…
1992
other
1991
A cell line designated RMG-II was established from the ascites of a patient with ovarian clear cell carcinoma. The chromosomal analysis revealed aneuploidy with a hypertetraploid modal number and 8 marker chromosomes. Radioimmunoassay and i…
observational
1991
The DNA content in individual cells from 40 cases of histopathologically normal endometria, 15 of endometrial hyperplasia and 68 of endometrial adenocarcinoma was measured by flow cytometry. An aneuploid cell population was found in 50% of …
other
1990
Danazol, which is commonly employed in the treatment of endometriosis creates a low estrogen and high androgen condition by suppressing ovarian steroidogenesis. When a reproductive-aged woman suddenly develops low estrogen, even if it is re…
other
1986
The purpose of the study was to examine the penetration of cefoperazone (CPZ) into the exudate of retroperitoneal space after (semi-)radical hysterectomy in patients with uterine carcinoma and to evaluate the suitability of its prophylactic…