Flávia Cappello Donabela

observational 2017

PTGS2 down-regulation in cumulus cells of infertile women with endometriosis

Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2017.06.021

A deleterious effect of endometriosis on oocyte quality has been proposed. Evidence suggests that cumulus cells could be used as indirect biomarkers of oocyte quality. The PTGS2 gene, which encodes cyclooxygenase 2 (COX-2), is deregulated i…

other 2015

Higher SOD1 Gene Expression in Cumulus Cells From Infertile Women With Moderate and Severe Endometriosis

Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719115585146

It is questioned whether worsening of oocyte quality and oxidative stress (OS) are involved in the pathogenesis of infertility related to endometriosis and in compromised intracytoplasmic sperm injection (ICSI) outcomes. Cumulus cells (CCs)…

observational 2013

Endometriosis, endometrium, implantation and fallopian tube

·doi:10.1093/humrep/det211

Study question: To compare the pregnancy rate in patients submitted to FET (Frozen Embryos Transfer) of cleavage stage embryos (Group 1), or at the blastocyst stage (Group 2). Summary answer: Our data showed that the transfer of frozen blas…

2013

Expressão do gene PTGS2 (COX2) em células do cumulus de pacientes inférteis com endometriose e controles submetidas à ICSI

2013

Expressão do gene SOD1 em células do cumulus de mulheres inférteis com endometriose moderada e severa: biomarcador não invasivo de gestação clínica pós-ICSI

2011

Gene expression of aromatase (CYP19A1) and 3β-hydroxysteroid dehydrogenase in cumulus oophorus cells of endometriosis and control infertile patients submitted to ICSI

·doi:10.1016/j.fertnstert.2011.07.290

2011

PTGS2 gene expression (COX2) in cummulus oophorus cells of endometriosis and control infertile patients submitted to ICSI

·doi:10.1016/j.fertnstert.2011.07.909

2010

Influence of pituitary suppression and controlled ovarian hyperstimulation (COH) on oxidative stress markers of infertile patients with endometriosis and controls

·doi:10.1016/j.fertnstert.2010.07.793

lab-animal 2010

Posters * Endometriosis, Endometrium and Implantation

·doi:10.1093/humrep/de.25.s1.242

Introduction: Endometriosis, defined as the growth of endometrial tissue outside \nthe uterine cavity is a common gynaecological disorder affecting 10-15% \nof women in their reproductive years. It is a major clinical problem causing in- \n…

2010

Serum markers of oxidative stress in infertile women with endometriosis and controls

·doi:10.1016/j.fertnstert.2010.07.154