Melis GB

No ORCID on file · 43 papers in corpus
review 2025
Expert opinion on drug metabolism & toxicology ·doi:10.1080/17425255.2025.2499550

INTRODUCTION: Endometriosis is a chronic disease characterized by endometriotic cells implanted outside the uterus triggering a chronic inflammatory state. Estradiol stimulates the endometriotic implants, which overexpress estrogen receptor…

diagnostic-accuracy 2019
The British journal of radiology ·doi:10.1259/bjr.20180548

OBJECTIVE:: Some recent studies have explored how the experience in the observers change their performance in the endometriosis detection using MRI but the effects of the clinical information remains uncertain. The purpose of this study was…

review 2016
Expert opinion on drug metabolism & toxicology ·doi:10.1517/17425255.2016.1171316

INTRODUCTION: Suppression of sex-steroid secretion is required in a variety of gynecological conditions. This can be achieved using gonadotropin releasing hormone (GnRH) agonists that bind pituitary gonadotropin receptors and antagonize the…

meta-analysis 2015
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology ·doi:10.1002/uog.15662

OBJECTIVES: To review the diagnostic accuracy of transvaginal ultrasound (TVS) in the preoperative detection of rectosigmoid endometriosis in patients with clinical suspicion of deep infiltrating endometriosis (DIE), comparing enhanced (E-T…

meta-analysis 2015
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology ·doi:10.1002/uog.15667

OBJECTIVE: To review the diagnostic accuracy of transvaginal ultrasound (TVS) in the preoperative detection of endometriosis in the uterosacral ligaments (USL), rectovaginal septum (RVS), vagina and bladder in patients with clinical suspici…

other 2015
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.3109/09513590.2015.1006617

Deep endometriosis involvement of the bladder is uncommon but it is symptomatic in most of the cases. Although laparoscopic excision is very effective, some patients with no pregnancy desire require a medical approach. We performed a pilot …

review 2015
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.3109/09513590.2015.1062868

Infertility is a common problem in patients with endometriosis and the involved mechanisms are still not completely known. The management of infertility in endometriosis patients includes surgery as well as assisted reproductive technology.…

review 2014
Acta radiologica (Stockholm, Sweden : 1987) ·doi:10.1177/0284185114526086

Several imaging options are available today to diagnose endometriosis. Currently, the two techniques most used are sonography and magnetic resonance imaging (MRI). Three-dimensional (3D) sonography has proved to be particularly sensitive in…

diagnostic-accuracy 2014
Human Reproduction ·doi:10.1093/humrep/deu054

STUDY QUESTION: In the use of 'tenderness-guided' transvaginal ultrasound, is the diagnostic accuracy of three-dimensional (3D) ultrasonography better than two-dimensional (2D) ultrasonography in the identification of deep endometriosis? S…

diagnostic-accuracy 2013
European radiology ·doi:10.1007/s00330-013-3013-9

OBJECTIVE: To assess the diagnostic confidence of multiple readers in the magnetic resonance imaging (MRI) diagnosis of endometriosis. METHODS: Sixty-five patients (mean age 33; range 19-45 years) who had undergone MRI were retrospectively…

other 2013
Journal of medical ultrasonics (2001) ·doi:10.1007/s10396-013-0514-8

OBJECTIVE: To compare two different methods (manual sampling of the entire cyst and semi-automated spherical sampling from the central part of the cyst) for calculating the mean gray value (MGV) from the cystic content in endometriomas usin…

review 2013
Minerva ginecologica

The imaging techniques have a fundamental role in the diagnosis of endometriosis. Ovarian endometriosis (endometrioma) and deep endometriosis can be recognized using transvaginal ultrasound and/or magnetic resonance imaging (MRI). Although …

review 2012
Obstetrics and Gynecology International ·doi:10.1155/2012/869191

Endometriosis is a common cause of pelvic pain and infertility. The majority of women report symptoms since adolescence, and there are rare cases of endometriosis in premenarchal age patients. Symptoms in adolescence are similar to those in…

other 2012
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology ·doi:10.1002/uog.12292

OBJECTIVES: To investigate differences in tissue characterization using three-dimensional sonographic mean gray value (MGV) between retrocervical and rectosigmoid deeply infiltrating endometriosis, and to assess intra- and interobserver con…

diagnostic-accuracy 2011
Maturitas ·doi:10.1016/j.maturitas.2010.09.013

In this study we aimed to assess the diagnostic accuracy of transvaginal ultrasound for assigning a specific diagnosis to benign adnexal masses in pre- and postmenopausal women. The study comprised 2146 adnexal masses in 1980 women. 1420 wo…

nonrandomized-trial 2009
Fertility and sterility ·doi:10.1016/j.fertnstert.2009.03.035

OBJECTIVE: To estimate the diagnostic value of transvaginal ultrasonography in the detection of pelvic adhesions in women suspected of having endometriomas at ultrasonography. DESIGN: Prospective observational study. SETTING: Academic Dep…

diagnostic-accuracy 2009
Journal of women's health (2002) ·doi:10.1089/jwh.2008.0997

OBJECTIVE: To evaluate the reproducibility and the accuracy of B-mode ultrasonographic features of three different kinds of benign ovarian cysts: ovarian endometrioma, mature teratoma, and serous cyst. METHODS: Digitally stored B-mode sono…

other 2009
Fertility and sterility ·doi:10.1016/j.fertnstert.2009.01.124
2009
other 2009
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine ·doi:10.7863/jum.2009.28.3.408
case-report 2009
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine ·doi:10.7863/jum.2009.28.8.1061

OBJECTIVE: The purpose of this presentation is to investigate the potential role of 3-dimensional (3D) sonography in the assessment of deep endometriosis. METHODS: Cases of deep endometriosis are presented to illustrate the spectrum of app…

diagnostic-accuracy 2008
Human Reproduction ·doi:10.1093/humrep/den293

BACKGROUND: The aim was to evaluate the diagnostic accuracy of transvaginal tenderness-guided ultrasonography in the identification of location of deep endometriosis. METHODS: Consecutive women scheduled for surgery in our Department for c…

2008
diagnostic-accuracy 2007
Fertility and sterility ·doi:10.1016/j.fertnstert.2006.12.060

OBJECTIVE: To determine the accuracy of transvaginal ultrasonography (TVUS) using a modified "tenderness-guided" approach in the diagnosis of deep endometriosis of the cul-de-sac, retrocervical region, and rectovaginal septum. DESIGN: Pros…

case-report 2007
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.06.054

OBJECTIVE: To report a case of endometrioid adenocarcinoma that arose in endometriosis mimicking colorectal cancer in a young woman with a Müllerian anomaly. DESIGN: A case report. SETTING: A university hospital. PATIENT(S): A 31-year-ol…