Wen-Jie Zhou

No ORCID on file · 28 papers in corpus
lab-animal 2016
Macrophages promote the growth and invasion of endometrial stromal cells by downregulating IL-24 in endometriosis
Reproduction (Cambridge, England) ·doi:10.1530/rep-16-0278

Macrophages play an important role in the origin and development of endometriosis. Estrogen promoted the growth of decidual stromal cells (DSCs) by downregulating the level of interleukin (IL)-24. The aim of this study was to clarify the ro…

lab-animal 2015
Blocking IL-22, a potential treatment strategy for adenomyosis by inhibiting crosstalk between vascular endothelial and endometrial stromal cells
American journal of translational research

Our previous work has demonstrated that interleukin-22 (IL-22) enhances the invasiveness of endometrial stromal cells (ESCs) of adenomyosis in an autocrine manner. In the present study, we further investigated whether IL-22 mediated crossta…

lab-animal 2015
TLR4 Activation Promotes the Secretion of IL-8 Which Enhances the Invasion and Proliferation of Endometrial Stromal Cells in an Autocrine Manner via the FAK Signal Pathway
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.12425

PROBLEM: Chronic inflammation is important for the occurrence of endometriosis, but the molecular mechanisms are still poorly understood. TLR4 is not only expressed on immune cells but is also present in the human endometrium, and its regul…