{"paper_id":"ad74a3c8-b93f-43be-bda3-102cbd66d503","body_text":"Interesting Image\nGiant Endometrioma of the Ovarian Mimicking Malignant Tumor\n- Rong Wang*\n- Ziyi Yang†,‡,§,∥\n- Shaoli Song†,‡,§,∥\nClinical Nuclear Medicine Publish Ahead of Print, November 11, 2026. | DOI: 10.1097/RLU.0000000000006748\n18F-FDG PET/CT findings of a giant ovarian endometrioma are exceedingly rare. We present a case of a 27-year-old woman with a giant pelvic cystic mass mimicking malignancy. 18F-FDG PET/CT revealed a massive cystic lesion occupying the entire abdominopelvic cavity, with mild internal septations and mild FDG uptake. Despite elevated tumor marker levels, weight loss, and suspicious imaging findings, the final histopathologic diagnosis was bilateral ovarian endometriomas.\nThis case report describes a rare 18F-FDG PET/CT finding of a giant ovarian endometrioma in a 27-year-old woman. She presented with a massive cystic lesion filling the entire abdominopelvic cavity, showing mild internal septations and mild FDG uptake. Clinical suspicion of malignancy was high because of elevated tumor marker levels, weight loss, and suspicious imaging features. However, histopathologic examination ultimately revealed bilateral ovarian endometriomas. This case highlights that large endometriomas can mimic ovarian cancer on imaging and underscores the importance of considering benign etiologies, even when tumor markers and imaging findings appear worrisome.\nText is machine generated and may contain inaccuracies. FAQ\nCopyright © 2026 Wolters Kluwer Health, LLC. All rights reserved.","source_license":"CC0","license_restricted":false}